Long non-coding RNA NEAT1 promotes proliferation, migration and invasion of human osteosarcoma cells
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چکیده
منابع مشابه
Silencing of the long non-coding RNA NEAT1 suppresses ovarian cancer cell proliferation, migration and invasion
Increasing evidence reveals that long noncoding RNAs (lncRNAs) are involved in the development of various human cancers including ovarian cancer. LncRNA nuclear enriched abundant transcript 1 (NEAT1) is an essential structural determinant of nuclear body paraspeckles. Although aberrant expression and prognostic value of NEAT1 has been recently reported in various human cancers, NEAT1 was not fu...
متن کاملLong non-coding RNA linc-ITGB1 promotes cell proliferation and migration in human hepatocellular carcinoma cells
Hepatocellular carcinoma (HCC) represents a major endpoint of chronic liver diseases and is the third leading cause of cancer-related mortality. Long intergenic non-coding RNA-integrin subunit β1 ITGB1 (linc-ITGB1) is a novel long non-coding RNA, which is implicated in the development and progression of human tumors. However, its involvement in hepatocarcinogenesis remains to be elucidated. In ...
متن کاملCTD-2020K17.1, a Novel Long Non-Coding RNA, Promotes Migration, Invasion, and Proliferation of Serous Ovarian Cancer Cells In Vitro
BACKGROUND Ovarian cancer is the most lethal malignant tumor of the female reproductive system, and the metastasis is one of the major factors that contribute to the poor outcome of patients with OC. Accumulating evidence indicates that lncRNAs are expressed and play important regulatory roles in ovarian cancer. MATERIAL AND METHODS Aberrant lncRNAs in primary ovarian cancer tissues (POCTs) and...
متن کاملHuman MALAT-1 long non-coding RNA is overexpressed in cervical cancer metastasis and promotes cell proliferation, invasion and migration.
PURPOSE Long non-coding RNAs (lncRNAs) have been shown to play a crucial role in the development as well as the prognosis of various human cancers, particularly in human metastasis associated lung adenocarcinoma transcript-1 (MALAT-1), which has been shown to be upregulated in some tumors. However, the role of MALAT-1 in cervical cancer (CC) is yet to be elucidated. This study aimed to establis...
متن کاملLong non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation.
Osteosarcoma is a malignant tumor of the skeletal system. Long non-coding RNAs (lncRNAs) have been shown to play significant role in osteosarcoma. The present study evaluated the effects and mechanism of lncRNA AK093407 in osteosarcoma. The study included human osteosarcoma cell line, U-2OS. Cell proliferation, viability, and apoptosis were measured using Ki-67 proliferation assay, MTT assay, a...
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ژورنال
عنوان ژورنال: International Journal of Medical Sciences
سال: 2018
ISSN: 1449-1907
DOI: 10.7150/ijms.25662